Crucial At-Home Female Hormone Test

• Chronically Painful PMS
• Amenorrhea
• Estrogen dominance symptoms
• DUB (dysfunctional uterine bleeding)
• Sexual dysfunction,
• Hypogonadism
• Fibrocystic breast disease
• Osteoporosis
• PCOS screening
• Infertility screening
• Menopausal symptoms
• Anovulation
• Screening for adrenal fatigue

The Crucial At-Home Female Hormones Test Is Encouraged If You Are Experiencing:

• nervousness, anxiety and irritability
• hyperactivity – you may find it hard to stay still and have a lot of nervous energy
• mood swings
• difficulty sleeping
• feeling tired all the time
• sensitivity to heat
• muscle weakness
• diarrhoea
• needing to pee more often than usual
• persistent thirst
• itchiness
• loss of interest in sex
• Fatigue
• Increased sensitivity to cold
• Constipation
• Dry skin
• Weight gain
• Puffy face
• Hoarseness
• Muscle weakness
• Elevated blood cholesterol level
• Muscle aches, tenderness and stiffness
• Pain, stiffness or swelling in your joints
• Heavier than normal or irregular menstrual periods
• Thinning hair
• Slowed heart rate
• Depression
• Impaired memory
• Enlarged thyroid gland (goiter)

At-Home Crucial Female Hormone Test Ranges

Testosterone (ng/dl)

Premenopausal - luteal: 18-39
Postmenopausal: 13-38
Postmenopausal - testosterone replacement:
29-224

DHEA-Sulfate

17 - 207 ng/dL

Estradiol

Premenopausal - luteal 51-302 ug/dL
Premenopausal - early follicular 30-92 ug/dL
Postmenopausal <10-26 ug/dL
Postmenopausal - estrogen replacement 32-472 ug/dL

Progesterone (ng/ml)

Premenopausal - luteal: 4.3-25.3 <0.1-0.9 0.5-4.3 5.2-65.3
Postmenopausal: <0.1-0.9 0.5-4.3 5.2-65.3
Oral Pg (100-300 mg): 0.5-4.3
Topical Pg (10-30 mg): 5.2-65.3

Cortisol (ug/ml)

Morning: 9.1-19.6
Evening/night: 3.3-8.9

Biomarkers tested

Estradiol (E2)

Estradiol is an estrogen and the primary sex hormone for females. It is important in regulating the reproductive cycles for females. It is released from ovaries and adrenal glands and plays a major role in the growth of women's reproductive tissues, including breasts, uterus, fallopian tubes, and vagina throughout life stages. This also affects other tissues including bone, fat, skin, liver, and brain. When assessing menopausal symptoms that may include hot flashes, mood disturbances, and aging skin, it is important to compare the relationship between estradiol and progesterone.

Males do have estradiol in their bodies but the amount compared to females is much lower. Estradiol is released from the testes and adrenal glands. Since males lack female anatomy, they must generate estrogen through a process involving aromatase, an enzyme that converts testosterone into estradiol. Estradiol has been shown in vitro to stop cell destruction, but its clinical importance in male sexual function and growth is lower than in females.

Progesterone (Pg)

Progesterone is a female hormone, released during ovulation by the ovaries. When a sperm fertilizes an egg, progesterone helps to prepare the uterus lining (endometrium) for the egg. If the egg is not fertilized, the level of progesterone decreases, and menstrual bleeding starts. During pregnancy the placenta releases high levels of progesterone, beginning at the end of the first trimester and continuing through birth. Pregnant women have progesterone levels almost 10 times higher than females who are not pregnant. Additionally, certain forms of cancer trigger elevated levels of progesterone in both men and women.

Testosterone

Testosterone is the primary sex hormone and anabolic steroid for males. Testosterone plays a key role in male reproductive tissue production, such as testes and prostate, as well as promoting secondary sexual characteristics, such as increased muscle and bone mass, and body hair growth. Female ovaries do produce testosterone in much smaller amounts compared to males. Testosterone development begins to increase dramatically during puberty and starts declining after age 30 or so.

DHEA Sulfate

DHEA sulfate is an androgen (male sex hormone) that is present in the blood of both men and women. It assists in the development of male secondary sexual characteristics at puberty and can be metabolized into testosterone and androstenedione (more potent androgens), or changed into estrogen (a female hormone). The outer layer of the adrenal glands, the adrenal cortex, is responsible for producing DHEA sulfate, while smaller amounts are produced in the testes and ovaries. Dehydroepiandrosterone sulfate secretion is controlled by the pituitary hormone adrenocorticotropic hormone (ACTH) and other pituitary factors. Since DHEA,s is primarily produced by the adrenal glands, it is a strong marker for adrenal function. Cancers, adrenal tumors, and hyperplasia can lead to the overproduction of DHEA sulfate. While elevated levels may not be noticed in adult men, they can lead to visible symptoms of virilization and amenorrhea.

Cortisol

Cortisol, the major adrenal glucocorticoid steroid hormone, is usually under feedback control by pituitary ACTH and the hypothalamus. Causes of low cortisol include pituitary failure or destruction, with resultant loss of ACTH to stimulate the adrenal, and metabolic errors or destruction of the adrenal gland itself (adrenogenital syndromes, tuberculosis, histoplasmosis). The diagnosis of hypoadrenalism usually requires confirmation with ACTH stimulation, due to the circadian rhythms of cortisol and other factors. Causes of increased cortisol, which may initially present as simply a loss of normal diurnal variation, include pituitary overproduction of ACTH, production of ACTH by a tumor (notably oat cell cancers), and adrenal adenomas.

Preparation: 10-12 hours fasting is required. Avoid anti-aging/anti-wrinkle facial creams for 3 days prior to testing as they may contain undisclosed hormones.

Test Results: 7-8 Days once the lab receives the specimen. May take longer based on weather, holiday or lab delays.

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